Arteta has missed four games with a hamstring injury while Cahill has been troubled by a foot problem for the past month.
Midfielder John Heitinga is doubtful after hobbling out of last week's win over Blackburn with a hamstring injury.
Jack Rodwell and Seamus Coleman are both pushing to start after substitute appearances last week but Louis Saha and Marouane Fellaini are long-term absentees.
Source: PA
Source: PA